Gene interactions and pathways from curated databases and text-mining

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MMP11 — RECK

Text-mined interactions from Literome

Liu et al., Oncogene 2002 (Lung Neoplasms) : In this study, we test the possibility that NSAIDs may up-regulate RECK to inhibit MMP activity
Liu et al., Cancer Res 2003 (Lung Neoplasms...) : In this study, we test the possibility that HDAC inhibitor may increase RECK expression to inhibit MMP activation and cancer cell invasion
Oh et al., Cancer Res 2004 (Melanoma) : TIMP-2 and Ala+TIMP-2 also suppress basal hMVEC migration via a time dependent mechanism mediated by enhanced expression of RECK , a membrane anchored MMP inhibitor , which, in turn, inhibits cell migration
Simizu et al., Cancer Res 2005 (Neoplasm Invasiveness) : RECK , a glycosylphosphatidylinositol (GPI) anchored glycoprotein, negatively regulates matrix metalloproteinases ( MMP ) , such as MMP-9, and inhibits tumor invasion and metastasis
Oh et al., Oncogene 2006 : We previously demonstrated that TIMP-2 increases the association of Crk with C3G and via subsequent activation of Rap1 enhances the expression of RECK , a membrane anchored MMP inhibitor
Paulissen et al., Mol Med 2006 (Asthma...) : mRNA expression profile of selected ADAM and ADAMTS proteinases ( ADAM-8, -9, -10, -12, -15, -17, and -33 ; ADAMTS-1, -2, -15, -16, -17, -18, and -19 ), their physiological inhibitors TIMP-1 and TIMP-3, and RECK , a membrane anchored MMP activity regulator , was obtained by RT-PCR analysis performed on cells collected by sputum induction from 21 patients with mild to moderate asthma and 17 healthy individuals
Lee et al., J Cell Biochem 2008 : Here, we examined the expression of RECK , a novel membrane anchored MMP inhibitor , in PSCs
Takagi et al., Cancer Res 2009 (Fibrosarcoma) : RECK , a glycosylphosphatidylinositol anchored glycoprotein, inhibits the enzymatic activities of some matrix metalloproteinases ( MMP ) , thereby suppressing tumor cell metastasis ; however, the detailed mechanism is still obscure
Walsh et al., Journal of cell communication and signaling 2012 : TIMP-2, the most studied member of the family, can both inhibit and activate MMPs directly, as well as inhibit MMP activity indirectly by upregulating expression of RECK , a membrane anchored MMP regulator