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MMP11 — RECK
Text-mined interactions from Literome
Liu et al., Oncogene 2002
(Lung Neoplasms) :
In this study, we test the possibility that NSAIDs may up-regulate
RECK to
inhibit MMP activity
Liu et al., Cancer Res 2003
(Lung Neoplasms...) :
In this study, we test the possibility that HDAC inhibitor may increase
RECK expression to
inhibit MMP activation and cancer cell invasion
Oh et al., Cancer Res 2004
(Melanoma) :
TIMP-2 and Ala+TIMP-2 also suppress basal hMVEC migration via a time dependent mechanism mediated by enhanced expression of
RECK , a membrane anchored
MMP inhibitor , which, in turn, inhibits cell migration
Simizu et al., Cancer Res 2005
(Neoplasm Invasiveness) :
RECK , a glycosylphosphatidylinositol (GPI) anchored glycoprotein, negatively
regulates matrix metalloproteinases ( MMP ) , such as MMP-9, and inhibits tumor invasion and metastasis
Oh et al., Oncogene 2006
:
We previously demonstrated that TIMP-2 increases the association of Crk with C3G and via subsequent activation of Rap1 enhances the expression of
RECK , a membrane anchored
MMP inhibitor
Paulissen et al., Mol Med 2006
(Asthma...) :
mRNA expression profile of selected ADAM and ADAMTS proteinases ( ADAM-8, -9, -10, -12, -15, -17, and -33 ; ADAMTS-1, -2, -15, -16, -17, -18, and -19 ), their physiological inhibitors TIMP-1 and TIMP-3, and
RECK , a membrane anchored
MMP activity
regulator , was obtained by RT-PCR analysis performed on cells collected by sputum induction from 21 patients with mild to moderate asthma and 17 healthy individuals
Lee et al., J Cell Biochem 2008
:
Here, we examined the expression of
RECK , a novel membrane anchored
MMP inhibitor , in PSCs
Takagi et al., Cancer Res 2009
(Fibrosarcoma) :
RECK , a glycosylphosphatidylinositol anchored glycoprotein,
inhibits the enzymatic activities of some
matrix metalloproteinases ( MMP ) , thereby suppressing tumor cell metastasis ; however, the detailed mechanism is still obscure
Walsh et al., Journal of cell communication and signaling 2012
:
TIMP-2, the most studied member of the family, can both inhibit and activate MMPs directly, as well as
inhibit MMP activity indirectly by upregulating expression of
RECK , a membrane anchored MMP regulator