Gene interactions and pathways from curated databases and text-mining

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REG1A — TNF

Text-mined interactions from Literome

Cheung et al., Diabetes 2000 (Insulin Resistance...) : In addition, TNF-alpha blockade reduced hepatic PTP activity toward tyrosine phosphorylated FAK by 70 %, and this was accounted for by immunodepletion of LAR
Wilhelm et al., Shock 2002 (Sepsis) : Although PTK was the predominant signaling pathway, inhibition of PTP only partially restored the TNF-alpha response to SAC-I
Ahmed et al., Am J Physiol Gastrointest Liver Physiol 2006 : SHP-1 and SHP-2 protein levels were unaltered by TNF or GH, and the GH-induced increase in SHP-1 PTP activity was not further increased by TNF
Wu et al., J Endocrinol Invest 2012 : The underlying molecular mechanism by which TNF-a regulates hepatic protein-tyrosine phosphatase (PTP)-1B expression is not well understood