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CASP3 — RENBP
Text-mined interactions from Literome
Peng et al., Med Sci Monit 2002
(Alzheimer Disease) :
AGE and SAC not only suppressed the generation of ROS but also
attenuated caspase-3 activation, DNA fragmentation, PARP cleavage and eventually protected against Ab-induced apoptosis
Jackson et al., Nutr Neurosci 2002
:
The purpose of the study was to determine whether dietary
aged garlic extract (AGE) , with known antioxidant properties and neuroprotection against Alzheimer 's beta-amyloid cytotoxicity,
inhibits the
caspase-3 activity in vitro ... We report that
AGE inhibits
caspase-3 in dose dependent manner
Kowluru et al., Life Sci 2005
(Diabetic Retinopathy) :
AGE-BSA induced their apoptosis by 55 %, and
activated caspase-3 by about 50 % compared to the cells incubated with unmodified BSA
Chen et al., Life Sci 2006
(Diabetic Retinopathy) :
The results showed that
AGE-BSA could
induce significantly the apoptosis of BRPs in a dose dependent manner compared with controls, associated with an increase in intracellular malondialdehyde level and
caspase-3 activity ; a decrease in intracellular catalase, SOD activities and Bcl-2/Bax ratio