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RHO — VASP
Text-mined interactions from Literome
Grosse et al., EMBO J 2003
:
VASP induced F-actin accumulation and SRF activation
require both functional
Rho and its effector mDia, and conversely, mDia mediated SRF activation is critically dependent on functional VASP
Howe et al., Biochim Biophys Acta 2004
:
Furthermore, while some hallmarks of cell migration and cytoskeletal organization require PKA activity ( e.g. activation of Rac and Cdc42 ; actin filament assembly ), others are inhibited by it ( e.g.
activation of
Rho and PAK ; interaction of
VASP with the c-Abl tyrosine kinase )