Gene interactions and pathways from curated databases and text-mining

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FAS — RNF19A

Text-mined interactions from Literome

Brenner et al., Cell Death Differ 1998 : Here, we demonstrate that Fas receptor triggered activation of the acidic sphingomyelinase, consumption of sphingomyelin, release of ceramide, and subsequent activation of JNK and p38-K are regulated by caspases
Ivanov et al., Oncogene 2000 (Melanoma) : Forced expression of a dominant negative form of p38 ( p38-ASP ) or treatment with p38 pharmacological inhibitor, SB203580, increases NF-kappaB activity, Fas expression and the levels of UVC induced apoptosis in late stage melanoma cells
Park et al., Mol Cancer Ther 2009 (Carcinoma, Renal Cell) : GST-MDA-7 killing was, in parallel, dependent on inactivation of extracellular signal regulated kinase 1/2 and on CD95 induced p38 mitogen activated protein kinase and c-jun NH ( 2 ) -terminal kinase-1/2 signaling
Juo et al., Mol Cell Biol 1997 : In this study Fas activated the stress-responsive mitogen activated protein kinases, p38 and JNK, within 2 h in Jurkat T lymphocytes but not the mitogen-responsive kinase ERK1 or pp70S6k