Gene interactions and pathways from curated databases and text-mining

◀ Back to WNT2

RPGR — WNT2

Text-mined interactions from Literome

Dann et al., Nature 2001 : Recently, an LDL-receptor related protein has been shown to function as a co-receptor for Wnt proteins and to bind to a Frizzled CRD in a Wnt dependent manner
Kameya et al., Hum Mol Genet 2002 (Disease Models, Animal...) : The CRD is essential for Wnt binding and signaling
Noubissi et al., Cancer Res 2009 (Colorectal Neoplasms) : Wnt/beta-catenin signaling induces expression of an RNA binding protein, CRD-BP , which in turn binds and stabilizes GLI1 mRNA, causing an elevation of GLI1 expression and transcriptional activity
Bhat et al., J Cell Biochem 2010 : The Fz CRD is also critical for Wnt signaling, as a deletion of 29 amino acids in the 2nd cysteine loop resulted in the total loss of TCF-luciferase activation