Gene interactions and pathways from curated databases and text-mining

◀ Back to IFNG

IFNG — RPL17

Text-mined interactions from Literome

Li et al., Acta Biochim Biophys Sin (Shanghai) 2004 : The results suggested that GST-PD-1 could competently block the interaction between PD-L1 and PD-1 and increase the production of IL-2 and IFN-gamma of phytohemagglutinin activated T cells
Cai et al., Cell Immunol 2004 : PD-1 ligand blockade modestly enhanced the percentage of responding T cells and production of IFN-gamma in a primary response to myelin basic protein (MBP) in normal donors
Ariel et al., J Biol Chem 2005 (Inflammation...) : PD1 blocked T cell migration in vivo, inhibited tumor necrosis factor alpha and interferon-gamma secretion, and promoted apoptosis mediated by raft clustering
Maier et al., J Immunol 2007 (Hepatitis B, Chronic) : To determine whether PD-1 plays a role in the functional suppression of IFN-gamma secretion by CTLs, we treated HBV transgenic mice with blocking Abs specific for PD ligand (PD-L)1, the most widely expressed PD-1 ligand, and adoptively transferred HBV-specific CTLs. Treatment with anti-PD-L1 Abs resulted in a delay in the suppression of IFN-gamma producing CTLs and a concomitant increase in the absolute number of IFN-gamma producing CTLs in the liver
Wahl et al., Gastroenterology 2008 : In contrast, the PD-1/B7-H1 interaction inhibited proliferation and interferon-gamma release of effector/memory CD8 T blasts specifically restimulated by peptide pulsed HC
Babu et al., J Infect Dis 2009 (Filariasis...) : Blockade of CTLA-4 restored production of both IFN-gamma and IL-17, whereas PD-1 blockade restored IFN-gamma production only
Rosignoli et al., Clin Exp Immunol 2009 (HIV Infections) : The effect of PD-1 and PD-L1 blockade on proliferation and interferon (IFN)-gamma production was tested on eight HIV-1 ( + ) patients
Figueira et al., J Periodontol 2009 (Alveolar Bone Loss...) : These data show that PD-1 engagement could be involved in the modulation of IFN-gamma production by T cells in patients with chronic periodontitis