Gene interactions and pathways from curated databases and text-mining

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Pathways - manually collected, often from reviews:

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Cruz et al., J Leukoc Biol 2005 : We show that S6K2 is activated by IL-3 in the IL-3 dependent Ba/F3 cell line and that this is mediated by mTOR and its upstream activator PI-3K but not by the MAPK kinase/extracellular signal regulated kinase pathway
Magnuson et al., Biochem J 2012 : mTORC1 ( mammalian TORC1 ) phosphorylates and activates S6K1 and S6K2 , whose first identified substrate was rpS6 ( ribosomal protein S6 ), a component of the 40S ribosome