Gene interactions and pathways from curated databases and text-mining

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IL6 — S100B

Text-mined interactions from Literome

Reddy et al., J Biol Chem 2006 (Diabetes Mellitus, Type 2) : An inhibitor of Src kinase, PP2, significantly blocked S100B induced activation of Src kinase, mitogen activated protein kinases, transcription factors NF-kappaB and STAT3, superoxide production, tyrosine phosphorylation of Cav-1, VSMC migration, and expression of the pro-inflammatory genes monocyte chemotactic protein-1 and interleukin-6
Ponath et al., J Neuroimmunol 2007 : S100B induced IL-6 and TNF-alpha secretion was blocked by the use of RAGE siRNA specific for knocking down RAGE expression
Schmitt et al., Neurosci Res 2007 (Hypothermia) : In the presence of S100B hypothermia induced IL-6 release in primary astrocytes was significantly increased but reduced in BV-2 microglial cells and primary neurons
de Souza et al., Prog Neuropsychopharmacol Biol Psychiatry 2013 (Glioma) : Interleukin-6 induced S100B secretion is inhibited by haloperidol and risperidone
Piazza et al., Int J Immunopathol Pharmacol 2013 : Soluble RAGE ( sRAGE ) reduced S100B dependent secretion of TNF-alpha but did not decrease S100B dependent secretion of IL-6