Gene interactions and pathways from curated databases and text-mining

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SIRT3 — SOD2

Text-mined interactions from Literome

Qiu et al., Cell Metab 2010 : Calorie restriction reduces oxidative stress by SIRT3 mediated SOD2 activation
Chen et al., EMBO Rep 2011 : Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS ... Mitochondrial deacetylase SIRT3 binds to, deacetylates and activates SOD2
Mendelsohn et al., Rejuvenation Res 2013 : Forced expression of SIRT3 , which activates the reactive oxygen species ( ROS ) scavenger superoxide dismutase 2 (SOD2) by de-acetylation to reduce oxidative stress, functionally rejuvenates mouse HSCs