Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Sampath et al., Neoplasia (New York, N.Y.) 2013 : GDC-0980 , a dual PI3K/mTOR inhibitor , was found to reduce micro-CT angiography vascular density, while VSI MRI demonstrated a significant reduction in vessel density and an increase in mean vessel size, consistent with a loss of small functional vessels and a substantial antivascular response
Wang et al., Oncogene 2012 (Ovarian Neoplasms) : LY294002 and GDC-0941 , inhibitors of PI3K, or Rapamycin, an inhibitor of PI3K downstream target mTOR , can reverse the effects of Gab2 on migration and invasion