Gene interactions and pathways from curated databases and text-mining

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EGF — SLC2A2

Text-mined interactions from Literome

Mischoulon et al., J Cell Physiol 1992 : EGF, a potent liver mitogen, although causing a threefold induction of GLUT-1, was found to have no effect on GLUT-2 expression, suggesting that the increase in GLUT-2 seen in regenerating liver is not due to EGF
Lee et al., Am J Physiol Gastrointest Liver Physiol 2006 (MAP Kinase Signaling System) : Therefore, this study examined the effect of EGF on GLUT2 and its related signal cascades in primary cultured chicken hepatocytes ... In addition, the EGF induced decrease in GLUT2 protein expression was inhibited by staurosporine, H-7, or bisindolylmaleimide I ( PKC inhibitors ), PD-98059 ( a MEK inhibitor ), SB-203580 ( a p38 MAPK inhibitor ), and SP-600125 ( a JNK inhibitor ), suggesting a role of both PKC and MAPKs ( p44/42 MAPK, p38 MAPK, and JNK )