Gene interactions and pathways from curated databases and text-mining

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IL4 — SLPI

Text-mined interactions from Literome

Ura et al., Endocr J 2000 : A spontaneous increase in alkaline phosphatase (ALP) activity in the cells after plating was inhibited by IL-4 or IL-13, and both cytokines blunted an increase in ALP activity by human parathyroid hormone (PTH) ( 1-34 )
Frost et al., Bone 2001 : Furthermore, IL-13 and IL-4 dose-dependently enhanced alkaline phosphatase (ALP) activity, but did not affect osteocalcin or collagen type I synthesis ... However, the antibodies did not affect the IL-4/-13 induced inhibition of [ ( 3 ) H ] -thymidine incorporation or the stimulation of alkaline phosphatase (ALP) , suggesting that IL-4Ralpha does not mediate these effects of IL-4/-13 in hOBs