Krause et al., Dev Biol 2004
:
The identification of a new Tbx5/4-specific binding factor further suggests a novel mechanism for Tbx transcription factor regulation in development and disease
Camarata et al., J Cell Biol 2006
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These studies reveal a previously unknown mechanism for Tbx transcription factor regulation in vertebrate limb and heart development and provide a better understanding of the molecular basis of hand/heart birth defects associated with Tbx5 mutations
Bimber et al., Dev Biol 2007
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The shuttling between nuclear and cytoplasmic sites reveals a novel mechanism for Tbx transcription factor regulation in chicken heart development allowing new insights for a better understanding of the molecular basis of hand/heart birth defects associated with TBX5 mutations
Platonova et al., Cell Tissue Res 2007
(Abnormalities, Multiple...) :
TBX3 , the gene mutated in ulnar-mammary syndrome (UMS), is involved in the production of a transcription factor of the T-box family, known to inhibit transcription from the p14ARF ( p19ARF in mouse ) promoter in fibroblasts and to contribute to cell immortalization