Krejci et al., PloS one 2008
(Bone Diseases, Developmental) :
Although the mechanisms of FGFR3 action in cartilage are not completely understood, it is believed that the STAT1 transcription factor plays a central role in pathogenic FGFR3 signaling
Lluis et al., Proc Natl Acad Sci U S A 2011
:
In addition, during reprogramming of NPCs into induced pluripotent stem cells, the silencing of Tcf3 increased AcH3 and decreased the number of H3K9me3 positive heterochromatin foci early and long before reactivation of the endogenous stem cell genes