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CA2 — TERF2IP

Text-mined interactions from Literome

Oestreich et al., J Biol Chem 2009 (Calcium Signaling) : Here we demonstrate that PLCepsilon phosphatidylinositol 4,5-bisphosphate hydrolytic activity and PLCepsilon stimulated Rap1 GEF activity are both required for PLCepsilon mediated enhancement of sarcoplasmic reticulum Ca2+ release and that PLCepsilon significantly enhances Rap activation in response to betaAR stimulation in the heart
Guidetti et al., Biochem J 2013 : In blood platelets the small GTPase Rap1b is activated by cytosolic Ca2+ and promotes integrin aIIbß3 inside-out activation and platelet aggregation
Kawasaki et al., Proc Natl Acad Sci U S A 1998 : We propose that CalDAG-GEF proteins have a critical neuronal function in determining the relative activation of Ras and Rap1 signaling induced by Ca2+ and DAG mobilization