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TLR2 — TLR7
Text-mined interactions from Literome
Sel et al., J Immunol 2007
(Asthma...) :
These data indicate that TLR-3 or
TLR-7 activation by viral
TLR ligands has both preventive as well as suppressive effects on experimental asthma which is mediated by the additive effects of IL-12 and IL-10
Wu et al., Int J Immunogenet 2008
:
As an important member of TLRs,
TLR1 is
involved in the recognition of triacylated lipoproteins and mycobacterial products by binding to
TLR2 to form a heterodimer
Aravalli et al., Journal of neuroinflammation 2008
(Histoplasmosis) :
Furthermore, Yps3p induced
TLR2 signaling was
suppressed by vaccinia virus encoded
TLR inhibitors
Regueiro et al., Infect Immun 2009
:
We showed that Klebsiella induced
TLR2 and TLR4 upregulation was
dependent on
TLR activation
So et al., Glia 2009
(Cardiovirus Infections) :
More importantly,
TLR3 was
required for TMEV induced early
TLR2 upregulation in primary astrocytes leading to the production of TLR2 dependent cytokines such as IL-6
Chamorro et al., J Immunol 2009
:
TLR triggering on tolerogenic dendritic cells
results in
TLR2 up-regulation and a reduced proinflammatory immune program
Messlik et al., J Proteome Res 2009
(Chronic Disease...) :
The aim of this study was to characterize the
role of
TLR2 or TLR4 deficiency in epithelial cell stress responses under noninflamed and inflamed conditions using TLR-deficient mice and
TLR ( -/- ) cross bred IL-10-deficient mice as a model for genetically driven experimental colitis
Stridh et al., Journal of neuroinflammation 2011
(Hypoxia-Ischemia, Brain) :
In contrast,
TLR-2 was constitutively expressed in the brain and
TLR-2 deficiency
reduced HI injury
Kim et al., FEMS Microbiol Lett 2012
(Inflammation) :
L. plantarum genomic DNA mediated inhibition of signaling pathway and tumor necrosis factor-alpha was accompanied by the suppression of
toll-like receptor (TLR) 2 , TLR4, and TLR9 and the induction of interleukin-1 receptor associated kinase M, a negative
regulator of
TLR
Jia et al., Shanghai Kou Qiang Yi Xue 2011
:
CD14,
TLR4 receptors are involved in P.e-LPS effect and CD14,
TLR2 and TLR4 receptors are
involved in P.g-LPS effect in mouse osteoblast
Kwissa et al., Blood 2012
:
In the draining lymph nodes ( LNs ), consistent with the effects in blood, all
TLR-Ls induced expansion of CD14 ( + ) monocytes, but only
TLR7/8-L and TLR9-L expanded the activated CD14 ( + ) CD16 ( + ) cells
Kumar et al., PloS one 2012
(Infection...) :
Moreover, stimulation of the Muller glia with
TLR 2 , 3, 4, 5, 7 and 9 agonists
resulted in an increased
TLR expression as assayed by Western blot and flow cytometry
Wang et al., PloS one 2012
(Cell Transformation, Neoplastic...) :
TLR2 : TLR6 complexes
mediate the effect of NF-?B inactivation by CDA-2
Feriotti et al., PloS one 2013
(Disease Susceptibility...) :
Mannan or P. brasiliensis
induced decreased expression of MR and
TLR2 on A/J macrophages, whereas CR3,
TLR4 and TLR2 were reduced on B10.A cells
Römmler et al., J Immunol 2013
:
Whereas TLR9 induced TNF-a secretion of bone marrow derived macrophages and conventional dendritic cells was equally inhibited by INH-ODN 2088 and G-modified INH-ODNs such as INH-ODN 24888,
TLR7 induced TNF-a release and
TLR7- and TLR9 induced IL-12p40 release were significantly more impaired by G-modified INH-ODNs