Gene interactions and pathways from curated databases and text-mining

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TLR2 — TLR7

Text-mined interactions from Literome

Sel et al., J Immunol 2007 (Asthma...) : These data indicate that TLR-3 or TLR-7 activation by viral TLR ligands has both preventive as well as suppressive effects on experimental asthma which is mediated by the additive effects of IL-12 and IL-10
Wu et al., Int J Immunogenet 2008 : As an important member of TLRs, TLR1 is involved in the recognition of triacylated lipoproteins and mycobacterial products by binding to TLR2 to form a heterodimer
Aravalli et al., Journal of neuroinflammation 2008 (Histoplasmosis) : Furthermore, Yps3p induced TLR2 signaling was suppressed by vaccinia virus encoded TLR inhibitors
Regueiro et al., Infect Immun 2009 : We showed that Klebsiella induced TLR2 and TLR4 upregulation was dependent on TLR activation
So et al., Glia 2009 (Cardiovirus Infections) : More importantly, TLR3 was required for TMEV induced early TLR2 upregulation in primary astrocytes leading to the production of TLR2 dependent cytokines such as IL-6
Chamorro et al., J Immunol 2009 : TLR triggering on tolerogenic dendritic cells results in TLR2 up-regulation and a reduced proinflammatory immune program
Messlik et al., J Proteome Res 2009 (Chronic Disease...) : The aim of this study was to characterize the role of TLR2 or TLR4 deficiency in epithelial cell stress responses under noninflamed and inflamed conditions using TLR-deficient mice and TLR ( -/- ) cross bred IL-10-deficient mice as a model for genetically driven experimental colitis
Stridh et al., Journal of neuroinflammation 2011 (Hypoxia-Ischemia, Brain) : In contrast, TLR-2 was constitutively expressed in the brain and TLR-2 deficiency reduced HI injury
Kim et al., FEMS Microbiol Lett 2012 (Inflammation) : L. plantarum genomic DNA mediated inhibition of signaling pathway and tumor necrosis factor-alpha was accompanied by the suppression of toll-like receptor (TLR) 2 , TLR4, and TLR9 and the induction of interleukin-1 receptor associated kinase M, a negative regulator of TLR
Jia et al., Shanghai Kou Qiang Yi Xue 2011 : CD14, TLR4 receptors are involved in P.e-LPS effect and CD14, TLR2 and TLR4 receptors are involved in P.g-LPS effect in mouse osteoblast
Kwissa et al., Blood 2012 : In the draining lymph nodes ( LNs ), consistent with the effects in blood, all TLR-Ls induced expansion of CD14 ( + ) monocytes, but only TLR7/8-L and TLR9-L expanded the activated CD14 ( + ) CD16 ( + ) cells
Kumar et al., PloS one 2012 (Infection...) : Moreover, stimulation of the Muller glia with TLR 2 , 3, 4, 5, 7 and 9 agonists resulted in an increased TLR expression as assayed by Western blot and flow cytometry
Wang et al., PloS one 2012 (Cell Transformation, Neoplastic...) : TLR2 : TLR6 complexes mediate the effect of NF-?B inactivation by CDA-2
Feriotti et al., PloS one 2013 (Disease Susceptibility...) : Mannan or P. brasiliensis induced decreased expression of MR and TLR2 on A/J macrophages, whereas CR3, TLR4 and TLR2 were reduced on B10.A cells
Römmler et al., J Immunol 2013 : Whereas TLR9 induced TNF-a secretion of bone marrow derived macrophages and conventional dendritic cells was equally inhibited by INH-ODN 2088 and G-modified INH-ODNs such as INH-ODN 24888, TLR7 induced TNF-a release and TLR7- and TLR9 induced IL-12p40 release were significantly more impaired by G-modified INH-ODNs