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NOTCH1 — TNF

Pathways - manually collected, often from reviews:

• WikiPathways Notch Signaling Pathway: APH1A/APH1B/TNF/PSEN1/PSEN2/NCSTN → NOTCH2/NOTCH3/NOTCH4/NOTCH1 (activation)
  

Text-mined interactions from Literome

Ando et al., Oncogene 2003 (Arthritis, Rheumatoid) : We found that TNF induced the expression of Notch-1 , Notch-4, and Jagged-2 in RSF ... We found that TNF induced the expression of Notch-1, Notch-4 , and Jagged-2 in RSF
Acharyya et al., PloS one 2010 (Muscular Dystrophy, Duchenne) : TNF inhibits Notch-1 in skeletal muscle cells by Ezh2 and DNA methylation mediated repression : implications in duchenne muscular dystrophy
Jiao et al., Clin Dev Immunol 2012 (Arthritis, Rheumatoid) : The aim of this paper was to investigate whether Notch signaling mediated TNF-a induced cytokine production of cultured fibroblast-like synoviocytes ( FLSs ) from RA
Zhang et al., J Biol Chem 2012 (Inflammation...) : Importantly, overexpression of constituted active form of Notch1 ( NICD1 ) and Notch2 ( NICD2 ) suppressed production of TLR4 triggered proinflammatory cytokines such as TNF-a and IL-6 but promoted production of antiinflammatory cytokine IL-10, which is dependent on the PEST domain of NICD