Gene interactions and pathways from curated databases and text-mining

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CD8A — TNFSF9

Text-mined interactions from Literome

Blazar et al., J Immunol 2001 (Graft vs Host Disease...) : By quantifying graft-vs-host disease alloresponses in vivo, we demonstrate that both CD4 ( + ) and CD8 ( + ) T cell mediated alloresponses are regulated by 4-1BB/4-1BB ligand interactions to approximately the same extent
Cannons et al., J Immunol 2001 : To compare CD4 vs CD8 responses to 4-1BBL under similar conditions of antigenic stimulation, we performed MLRs with purified CD4 or CD8 responders from CD28 ( +/+ ) and CD28 ( -/- ) mice
Wen et al., J Immunol 2002 : To further understand the role of 4-1BBL in human T cell responses, we compared human CD4 and CD8 T cell responses to transfected human 4-1BBL plus TCR mediated stimulation
Dawicki et al., J Immunol 2004 : The 4-1BBL ( -/- ) and double knockout mice were similarly impaired in the CD8 T cell response, whereas OX40L ( -/- ) and double knockout mice were similarly impaired in the CD4 T cell response to both protein Ag and influenza virus
Fuse et al., J Immunol 2007 : Thus, 4-1BBL deficiency significantly affects the function, but not the number, of virus-specific CD8 ( + ) T cells during gammaherpesvirus latency, and its absence results in an increased viral burden