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PKD2 — TNNI3
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Cuello et al., Circ Res 2007
:
We conclude that increased myocardial
PKD activity
induces cardiac troponin I phosphorylation at Ser22/Ser23 and reduces myofilament Ca ( 2+ ) sensitivity, suggesting that altered PKD activity in disease may impact on contractile function
Goodall et al., J Biol Chem 2010
(Calcium Signaling) :
Consistent with an established
role of
PKD in targeting
cardiac troponin I (cTnI) , caPKD expression led to a marked decrease in contractile myofilament Ca ( 2+ ) sensitivity with an unexpected electrical stimulus dependence to this response