Gene interactions and pathways from curated databases and text-mining

◀ Back to PKD2

PKD2 — TNNI3

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Cuello et al., Circ Res 2007 : We conclude that increased myocardial PKD activity induces cardiac troponin I phosphorylation at Ser22/Ser23 and reduces myofilament Ca ( 2+ ) sensitivity, suggesting that altered PKD activity in disease may impact on contractile function
Goodall et al., J Biol Chem 2010 (Calcium Signaling) : Consistent with an established role of PKD in targeting cardiac troponin I (cTnI) , caPKD expression led to a marked decrease in contractile myofilament Ca ( 2+ ) sensitivity with an unexpected electrical stimulus dependence to this response