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MATK — TOPBP1
Text-mined interactions from Literome
Liu et al., Mol Cell Biol 2006
:
Despite their established requirement for Chk1 activation, the exact way in which
TopBP1 and Claspin
control Chk1 phosphorylation remains unclear
Séror et al., Cell cycle (Georgetown, Tex.) 2009
:
Depletion of PML,
TopBP1 , NBS1 or ATM
inhibit the activating phosphorylation of
Chk2
Tuul et al., PloS one 2013
:
By performing a genetic analysis of human HeLa cells and chicken B lymphoma DT40 cells, we found that heat induced
Chk1 Ser345 phosphorylation by ATR was largely
dependent on Rad9, Rad17,
TopBP1 and Claspin