Gene interactions and pathways from curated databases and text-mining

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MATK — TOPBP1

Text-mined interactions from Literome

Liu et al., Mol Cell Biol 2006 : Despite their established requirement for Chk1 activation, the exact way in which TopBP1 and Claspin control Chk1 phosphorylation remains unclear
Séror et al., Cell cycle (Georgetown, Tex.) 2009 : Depletion of PML, TopBP1 , NBS1 or ATM inhibit the activating phosphorylation of Chk2
Tuul et al., PloS one 2013 : By performing a genetic analysis of human HeLa cells and chicken B lymphoma DT40 cells, we found that heat induced Chk1 Ser345 phosphorylation by ATR was largely dependent on Rad9, Rad17, TopBP1 and Claspin