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GSN — TPM4

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Ciesielski-Treska et al., Eur J Cell Biol 1991 : Since tropomyosin stabilizes microfilaments and inhibits the severing activity of gelsolin , the toxin induced phosphorylation may counteract this inhibition resulting in severing of microfilaments and capping of short filaments
Khaitlina et al., FEBS J 2013 : Under nonpolymerizing conditions, binding of tropomyosin neither prevented the formation of a 2 : 1 actin-gelsolin complex, nor did it affect the nucleating activity of gelsolin in actin polymerization, likely as a result of competitive displacement of tropomyosin from gelsolin ... To evaluate the effect of tropomyosin on the actin filament severing activity of gelsolin , we measured both filamentous actin ( F-actin ) viscosity and the relative number concentrations of filaments after fragmentation, either by gelsolin alone or by gelsolin-tropomyosin complexes