Gene interactions and pathways from curated databases and text-mining

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AKT1S1 — TSC1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Wolff et al., Mol Cell Biol 2011 (Anoxia) : We previously reported that mTORC1 regulation by hypoxia involves Redd1 and the Tsc1/Tsc2 complex
Yoshida et al., J Biol Chem 2011 : Taken together, our results suggest that the TSC complex plays an important role in redox-sensitive mTORC1 regulation and argues for the activation of mTORC1 in places other than the lysosome upon inhibition of the TSC complex