Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Gomez-MarĂ­n et al., Parasitol Res 2002 : Thus, IFN gamma blocks the activities of both THP1 and parasite sPLA2 and cPLA2 in membrane fractions, resulting in protection against active invasion by T. gondii
Mazzeo et al., Cytokine 2002 : The effect of NAC was specific for IL-12 p75, as NAC did not affect induction of MHC class II expression by IFN-gamma stimulated THP-1 cells
Takagi et al., Biochem Biophys Res Commun 2006 : When the amount of total CIITA mRNA in NHK was quantified at 6h after IFN-gamma-stimulation, the amount of CIITA mRNA detected in NHK did not differ from that seen in the B cell line Raji or the IFN-gamma stimulated macrophage cell line THP-1
Barnholt et al., J Immunol 2009 : This investigation demonstrates that adding adenosine to IFN-gamma stimulated murine RAW 264.7 and human THP-1 macrophages results in unique modulation of STAT1 serine and tyrosine phosphorylation events
Fleckner et al., Cytokine 1995 : In the monocytic cells, THP-1 , gamma 2 mRNA was highly induced by IFN-gamma , whereas in the B-cell line, Daudi, gamma 2 mRNA was transiently induced by IFN-alpha and poly ( I ) .poly ( C ), and not by IFN-gamma
Cramer et al., Cell Immunol 1997 (Leukemia, Monocytic, Acute) : Stimulation of the human macrophage cell line THP-1 with interferon-gamma (IFN-gamma) resulted in maximal induction of both Tap-1 and Tap-2 mRNA within 24 hr. Nuclear run-on analyses showed that the increased expression of Tap-1 and Tap-2 was controlled at the level of transcription
Heyes et al., Biochem J 1997 (Astrocytoma) : High activities of kynurenine 3-hydroxylase, kynureninase or 3-hydroxyanthranilate 3,4-dioxygenase were found in interferon-gamma stimulated macrophages, THP-1 cells and SKHEP1 cells, and these cells made large amounts of quinolinate when supplied with L-tryptophan, L-kynurenine, 3-hydroxykynurenine or 3-hydroxyanthranilate