Gene interactions and pathways from curated databases and text-mining

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TGFB1 — USF2

Text-mined interactions from Literome

Weigert et al., J Biol Chem 2004 : Overexpression of either USF-1 or USF-2 increased TGF-beta1 promoter activity 2-fold, which was prevented by mutation or deletion of the GlRE
Chen et al., J Biol Chem 2006 : Although transforming growth factor beta1 increased the USF1/USF2-E-box binding and P4Halpha ( I ) promoter activity, this up-regulatory effect can be largely prevented by USF1/USF2-specific short interference RNA
Kim et al., J Korean Med Sci 2008 : Overexpression of USF increased both the mRNA levels and protein levels of TGF-beta1 ... Overexpression of USF in FRTL-5 cells increased the expression of TGF-beta10 through specific binding to TGF-beta1 promoter ... However, the USF induced expression of TGF-beta1 did not cause G1 arrest
Li et al., American journal of physiology. Renal physiology 2010 : USF2 mediates glucose induced thrombospondin 1 expression and transforming growth factor-beta activity in MCs and plays a role in DN. Glycated proteins have been shown to accumulate in the kidneys of diabetic patients and contribute to DN