Gene interactions and pathways from curated databases and text-mining

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GP5 — VEGFA

Text-mined interactions from Literome

Funamoto et al., J Biol Chem 2000 : Signal transducer and activator of transcription 3 is required for glycoprotein 130 mediated induction of vascular endothelial growth factor in cardiac myocytes
Osugi et al., J Biol Chem 2002 : Previously, we have demonstrated that the activation of STAT3 is required for glycoprotein 130 mediated induction of VEGF in cardiac myocytes, but the functional importance of STAT3 as an angiogenic mediator remains to be determined
Hawkins et al., J Neurosci 2010 : Pharmacological activation of Src kinase activity mimicked the effects of VEGF on P-glycoprotein activity and Tyr-14 phosphorylation of caveolin-1
Hawkins et al., J Cereb Blood Flow Metab 2010 : Thus, VEGF and PKCbeta1 reduce P-glycoprotein activity by distinct mechanisms
Rucci et al., Cancer Res 2010 (Bone Neoplasms...) : Cell surface glycoprotein extracellular matrix metalloproteinase inducer ( EMMPRIN ) /CD147 induces metalloproteinases ( MMP ) and vascular endothelial growth factor ( VEGF ), which may support osteoclastic activity and increased incidence of breast cancer bone metastases
Forsten-Williams et al., BMC systems biology 2011 : VEGF also binds to extracellular matrix ( ECM ) and neuropilin ( NP ), a cell surface glycoprotein that enhances VEGF binding to VEGFR2 while inhibiting VEGF-VEGFR1 interactions
Hida et al., J Biochem 2013 (Neoplasms...) : We found that high levels of vascular endothelial growth factor in tumour conditioned medium may be responsible for upregulated P-glycoprotein expression