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PI3 — VPS11

Text-mined interactions from Literome

Nasuhoglu et al., Anal Biochem 2002 : Phosphatidylinositol 3,4,5-trisphosphate ( PIP ( 3 ) ) and the D3 isomers of PIP ( 2 ) are detected after treatment of cells with pervanadate ; in yeast, overexpression of a phosphatidylinositol 3-kinase ( VPS34 ) specifically increases phosphatidylinositol 3-phosphate (PI3P)
Backer et al., Biochem J 2008 : The regulation and function of Class III PI3Ks : novel roles for Vps34
Mallo et al., J Cell Biol 2008 : Vps34 , a PI3-kinase that associates with active Rab5, is responsible for PI(3)P formation on SCVs
Schu et al., Science 1993 : Overexpression of Vps34p resulted in an increase in PI 3-kinase activity, and this activity was specifically precipitated with antisera to Vps34p. VPS34 encodes a yeast PI 3-kinase, and this enzyme appears to regulate intracellular protein trafficking decisions