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IGF2 — WT1

Text-mined interactions from Literome

Idelman et al., J Biol Chem 2003 (Bone Neoplasms...) : In the presence of mutant p53, WT1 can not repress the IGF-IR promoter
Drummond et al., Science 1992 (Wilms Tumor) : Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1
Martinerie et al., Oncogene 1994 (Kidney Neoplasms...) : Our results suggest that the regulation of IGFII expression by WT1 and increase of novH in Wilms tumors might be interrelated and represent a key element in tumor development in human
Nichols et al., Cancer Res 1995 (Wilms Tumor) : WT1 induces expression of insulin-like growth factor 2 in Wilms ' tumor cells ... The induction of IGF2 is dramatically enhanced by WT1 mutants encoding an altered transactivation domain
Hirschfeld et al., In Vivo 1994 (Bone Neoplasms...) : Insulin-like growth factor-II plays a role in Wilm 's tumor , neuroblastoma, and rhabdomyosarcoma, either as a proliferation factor, a motility factor, or both
Drummond et al., Mol Cell Biol 1994 : We have identified WT1 [ +KTS ] binding sites in the insulin-like growth factor II gene and show that WT1 [ +KTS ] represses transcription from the insulin-like growth factor II P3 promoter
Zhou et al., Differentiation 1993 : The expression of WT1 was compared with insulin-like growth factor-II (IGF-II) and its receptor in the decidual since it has been shown that IGF-II gene transcription is repressed by WT1 in vitro
Ward et al., Gene 1995 : Two variant forms of WT1 repressed the two major Igf-2 promoters ( P2 and P3 ) in transient transfection assays