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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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FOXO1 — XBP1

Text-mined interactions from Literome

Vidal et al., Hum Mol Genet 2012 (Disease Models, Animal...) : At the mechanistic level, we observed that XBP1 deficiency led to augmented expression of Forkhead box O1 (FoxO1) , a key transcription factor regulating autophagy in neurons
Zhao et al., Cell Res 2013 : Thus, our findings link the dynamic process of autophagy to XBP-1u induced FoxO1 degradation
Zhao et al., Autophagy 2013 (Neoplasms) : X-box binding protein 1u (XBP1u) plays a critical role in FOXO1 degradation by recruiting FOXO1 to the 20S proteasome ... Thus, our findings support the hypothesis that the turnover of FOXO1 induced by MAPK1/3 and XBP1u is a critical factor regulating the autophagic process