Gene interactions and pathways from curated databases and text-mining

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PLCG1 — RAP2B

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: RAP2B → PLCG1 (increases, PLCG1 Activity, RAP2B Activity) Stope et al., Mol Cell Biol 2004*
    Evidence: Collectively, these data suggest that the EGF receptor triggers activation of Rap2B via PLC-gamma1 activation and tyrosine phosphorylation of RasGRP3 by c-Src, finally resulting in stimulation of PLC-epsilon.