The Genome Aggregation Database (gnomAD) - Genome and Exome Sample Coverage track
set shows various read-depth variant metrics calculated separately for exomes and genomes on a ~10%
subset of the v2.0.2 samples. Multiple exome capture methods and sequencing chemistries were used
for sequencing, so coverage varies between individuals across sites. This variation of coverage is
incorporated in this track.
This track includes several subtracks of average coverage metrics and sample percentage of coverage.
For more information on the processing pipeline and population annotations, see the following
and the 2.0.2 README.
The Average Sample Coverage graphs display the mean and median read depth of the
samples at each base position. The details page shows calculated sample percentages for the range
of sequence within the browser window.
The nX Coverage Percentage graphs display the percentage of samples whose read
depth is at least 1X, 5X, 10X, 15X, 20X, 25X, 30X, 50X, and 100X at each base position. The details
page shows calculated sample percentages for the range of sequence within the browser window.
The raw data can be explored interactively with the
Table Browser, or the Data Integrator. For
automated analysis, the data may be queried from our REST API, and the genome annotations are stored in files that
can be downloaded from our download server, subject
to the conditions set forth by the gnomAD consortium (see below). Coverage values
for the genome are in bigWig files in
the coverage/ subdirectory. Variant VCFs can be found in the vcf/ subdirectory.
The data can also be found directly from the gnomAD downloads page. Please refer to
our mailing list archives for questions, or our Data Access FAQ for more information.
More information about using and understanding the gnomAD data can be found in the
gnomAD FAQ site.
Thanks to the Genome Aggregation
Database Consortium for making these data available. The data are released under the ODC Open Database License
(OBdL) as described here.
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