Gene interactions and pathways from curated databases and text-mining

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SP1 — XRCC5

Pathways - manually collected, often from reviews:

  • FastForward regulation: SP1 → XRCC5 (transcriptional regulation, unknown)
    Evidence: DNABINDING

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Rossi et al., J Gen Virol 2006 : It was also found that, in cell-free extracts, TCF-4 prevented dsDNA dependent protein kinase (DNA-PK) mediated Sp1 phosphorylation
Ludwig et al., Gene 1997 : Ku80 gene expression is Sp1 dependent and sensitive to CpG methylation within a novel cis element