Description: Homo sapiens cyclin-dependent kinase 17 (CDK17), transcript variant 2, mRNA. RefSeq Summary (NM_001170464): The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It has similarity to a rat protein that is thought to play a role in terminally differentiated neurons. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jul 2010]. Transcript (Including UTRs) Position: hg19 chr12:96,672,039-96,794,366 Size: 122,328 Total Exon Count: 16 Strand: - Coding Region Position: hg19 chr12:96,674,548-96,728,614 Size: 54,067 Coding Exon Count: 15
Body Weight Damien C Croteau-Chonka et al. Obesity (Silver Spring, Md.) 2011, Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women., Obesity (Silver Spring, Md.).
[PubMed 20966902]
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF00069 - Protein kinase domain PF07714 - Protein tyrosine kinase PF12330 - Haspin like kinase domain PF14531 - Kinase-like
SCOP Domains: 56112 - Protein kinase-like (PK-like)
ModBase Predicted Comparative 3D Structure on Q00537-2
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
