Human Gene PI4KB (uc001exu.3)
Description: Homo sapiens phosphatidylinositol 4-kinase, catalytic, beta (PI4KB), transcript variant 3, mRNA.
Transcript (Including UTRs)
Position: hg19 chr1:151,264,273-151,300,191 Size: 35,919 Total Exon Count: 11 Strand: -
Coding Region
Position: hg19 chr1:151,265,328-151,288,957 Size: 23,630 Coding Exon Count: 10
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Primer design for this transcript
Genetic Association Studies of Complex Diseases and Disorders
Comparative Toxicogenomics Database (CTD)
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF00454 - Phosphatidylinositol 3- and 4-kinase
SCOP Domains: 56112 - Protein kinase-like (PK-like)
ModBase Predicted Comparative 3D Structure on Q9UBF8-2
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Descriptions from all associated GenBank mRNAs
AB005910 - Homo sapiens mRNA for phosphatidylinositol 4-kinase, complete cds.DI487055 - KR 1020100056450-A/151: DSRNA FOR TREATING VIRAL INFECTION.JD114171 - Sequence 95195 from Patent EP1572962.AL832188 - Homo sapiens mRNA; cDNA DKFZp686O1820 (from clone DKFZp686O1820).BC000029 - Homo sapiens phosphatidylinositol 4-kinase, catalytic, beta, mRNA (cDNA clone MGC:1921 IMAGE:3508885), complete cds.AK054691 - Homo sapiens cDNA FLJ30129 fis, clone BRACE1000131.AJ011121 - Homo sapiens mRNA for phosphatidylinositol 4-kinase (NPIK-A).AJ011122 - Homo sapiens mRNA for phosphatidylinositol 4-kinase (NPIK-B).AJ011123 - Homo sapiens mRNA for phosphatidylinositol 4-kinase (NPIK-C).BC040300 - Homo sapiens phosphatidylinositol 4-kinase, catalytic, beta, mRNA (cDNA clone MGC:42391 IMAGE:4821417), complete cds.JD420600 - Sequence 401624 from Patent EP1572962.JD519242 - Sequence 500266 from Patent EP1572962.JD347385 - Sequence 328409 from Patent EP1572962.JD109251 - Sequence 90275 from Patent EP1572962.DI487091 - KR 1020100056450-A/187: DSRNA FOR TREATING VIRAL INFECTION.JD098293 - Sequence 79317 from Patent EP1572962.JD489505 - Sequence 470529 from Patent EP1572962.JD217566 - Sequence 198590 from Patent EP1572962.JD108370 - Sequence 89394 from Patent EP1572962.JD159179 - Sequence 140203 from Patent EP1572962.DI487042 - KR 1020100056450-A/138: DSRNA FOR TREATING VIRAL INFECTION.JD469347 - Sequence 450371 from Patent EP1572962.JD426209 - Sequence 407233 from Patent EP1572962.U81802 - Human PtdIns 4-kinase (PI4Kb) mRNA, complete cds.JD426239 - Sequence 407263 from Patent EP1572962.JD324828 - Sequence 305852 from Patent EP1572962.JD151226 - Sequence 132250 from Patent EP1572962.JD294613 - Sequence 275637 from Patent EP1572962.JD200886 - Sequence 181910 from Patent EP1572962.JD204978 - Sequence 186002 from Patent EP1572962.JD444851 - Sequence 425875 from Patent EP1572962.AK294606 - Homo sapiens cDNA FLJ57971 complete cds, highly similar to Phosphatidylinositol 4-kinase beta (EC 2.7.1.67).JD328275 - Sequence 309299 from Patent EP1572962.JD343850 - Sequence 324874 from Patent EP1572962.JD055549 - Sequence 36573 from Patent EP1572962.KJ905268 - Synthetic construct Homo sapiens clone ccsbBroadEn_14765 PI4KB gene, encodes complete protein.AB590088 - Synthetic construct DNA, clone: pFN21AB5785, Homo sapiens PI4KB gene for phosphatidylinositol 4-kinase, catalytic, beta, without stop codon, in Flexi system.DI487085 - KR 1020100056450-A/181: DSRNA FOR TREATING VIRAL INFECTION.DI487058 - KR 1020100056450-A/154: DSRNA FOR TREATING VIRAL INFECTION.DI487023 - KR 1020100056450-A/119: DSRNA FOR TREATING VIRAL INFECTION.AK311292 - Homo sapiens cDNA, FLJ18334.DI487043 - KR 1020100056450-A/139: DSRNA FOR TREATING VIRAL INFECTION.DI487087 - KR 1020100056450-A/183: DSRNA FOR TREATING VIRAL INFECTION.DI487025 - KR 1020100056450-A/121: DSRNA FOR TREATING VIRAL INFECTION.CU691848 - Synthetic construct Homo sapiens gateway clone IMAGE:100020097 5' read PI4KB mRNA.DI487066 - KR 1020100056450-A/162: DSRNA FOR TREATING VIRAL INFECTION.DI487030 - KR 1020100056450-A/126: DSRNA FOR TREATING VIRAL INFECTION.DI487076 - KR 1020100056450-A/172: DSRNA FOR TREATING VIRAL INFECTION.DI487099 - KR 1020100056450-A/195: DSRNA FOR TREATING VIRAL INFECTION.
Biochemical and Signaling Pathways
Other Names for This Gene
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_001198774.1
exon count:
11 CDS single in 3' UTR:
no
RNA size:
3934
ORF size:
2406 CDS single in intron:
no
Alignment % ID:
99.97
txCdsPredict score:
4931.00 frame shift in genome:
no
% Coverage:
100.00
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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