ID:MYO1D_HUMAN DESCRIPTION: RecName: Full=Unconventional myosin-Id; FUNCTION: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity). SUBUNIT: Binds calmodulin through its IQ motifs (By similarity). TISSUE SPECIFICITY: Expressed in many tissues. Highest levels in brain, followed by lung and ovary; expression is lowest in spleen. SIMILARITY: Contains 2 IQ domains. SIMILARITY: Contains 1 myosin head-like domain. CAUTION: Represents a unconventional myosin. This protein should not be confused with the conventional myosin-1 (MYH1). SEQUENCE CAUTION: Sequence=BAA34447.2; Type=Erroneous initiation;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF00612 - IQ calmodulin-binding motif PF00063 - Myosin head (motor domain) PF06017 - Unconventional myosin tail, actin- and lipid-binding
ModBase Predicted Comparative 3D Structure on O94832
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0007018 microtubule-based movement GO:0010923 negative regulation of phosphatase activity GO:0030900 forebrain development GO:0051641 cellular localization GO:0061502 early endosome to recycling endosome transport
US Server
