Human Gene SLFN5 (ENST00000299977.9) from GENCODE V44
Description: Homo sapiens schlafen family member 5 (SLFN5), transcript variant 1, mRNA. (from RefSeq NM_144975)
Gencode Transcript: ENST00000299977.9
Gencode Gene: ENSG00000166750.10
Transcript (Including UTRs)
Position: hg38 chr17:35,243,072-35,273,655 Size: 30,584 Total Exon Count: 5 Strand: +
Coding Region
Position: hg38 chr17:35,258,691-35,265,888 Size: 7,198 Coding Exon Count: 4
Data last updated at UCSC: 2023-08-18 00:09:47
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: SLFN5_HUMAN
DESCRIPTION: RecName: Full=Schlafen family member 5;
FUNCTION: May have a role in hematopoietic cell differentiation (By similarity).SIMILARITY: Belongs to the Schlafen family.
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR007421 - ATPase_AAA-4
IPR018647 - DUF2075
Pfam Domains: PF04326 - Putative DNA-binding domain
PF09848 - Uncharacterized conserved protein (DUF2075)
ModBase Predicted Comparative 3D Structure on Q08AF3
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AK303632 - Homo sapiens cDNA FLJ52101 complete cds.BX647942 - Homo sapiens mRNA; cDNA DKFZp686A2051 (from clone DKFZp686A2051).AK054668 - Homo sapiens cDNA FLJ30106 fis, clone BNGH41000190, weakly similar to Rattus norvegicus schlafen-4 (SLFN-4) mRNA.AK303299 - Homo sapiens cDNA FLJ52100 complete cds.BC021238 - Homo sapiens schlafen family member 5, mRNA (cDNA clone IMAGE:3636653), complete cds.JD339466 - Sequence 320490 from Patent EP1572962.BC125200 - Homo sapiens schlafen family member 5, mRNA (cDNA clone MGC:150611 IMAGE:40123369), complete cds.BC125201 - Homo sapiens schlafen family member 5, mRNA (cDNA clone MGC:150612 IMAGE:40123372), complete cds.JD373452 - Sequence 354476 from Patent EP1572962.CU676886 - Synthetic construct Homo sapiens gateway clone IMAGE:100017043 5' read SLFN5 mRNA.DQ896183 - Synthetic construct Homo sapiens clone IMAGE:100010643; FLH190969.01L; RZPDo839F1266D schlafen family member 5 (SLFN5) gene, encodes complete protein.KJ906443 - Synthetic construct Homo sapiens clone ccsbBroadEn_16113 SLFN5 gene, encodes complete protein.DQ892934 - Synthetic construct clone IMAGE:100005564; FLH190973.01X; RZPDo839F1276D schlafen family member 5 (SLFN5) gene, encodes complete protein.KJ895722 - Synthetic construct Homo sapiens clone ccsbBroadEn_05116 SLFN5 gene, encodes complete protein.AL832814 - Homo sapiens mRNA; cDNA DKFZp667B2124 (from clone DKFZp667B2124).AK075116 - Homo sapiens cDNA FLJ90635 fis, clone PLACE1003644.JD344108 - Sequence 325132 from Patent EP1572962.JD266535 - Sequence 247559 from Patent EP1572962.JD266536 - Sequence 247560 from Patent EP1572962.JD498300 - Sequence 479324 from Patent EP1572962.JD498301 - Sequence 479325 from Patent EP1572962.JD178835 - Sequence 159859 from Patent EP1572962.JD020900 - Sequence 1924 from Patent EP1572962.JD030469 - Sequence 11493 from Patent EP1572962.JD030280 - Sequence 11304 from Patent EP1572962.JD194607 - Sequence 175631 from Patent EP1572962.JD105922 - Sequence 86946 from Patent EP1572962.JD517624 - Sequence 498648 from Patent EP1572962.JD401778 - Sequence 382802 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: ENST00000299977.1, ENST00000299977.2, ENST00000299977.3, ENST00000299977.4, ENST00000299977.5, ENST00000299977.6, ENST00000299977.7, ENST00000299977.8, NM_144975, Q08AF2, Q08AF3, Q8WU54, Q96A82, SLFN5_HUMAN, uc002hjf.1, uc002hjf.2, uc002hjf.3, uc002hjf.4, uc002hjf.5, uc002hjf.6UCSC ID: ENST00000299977.9RefSeq Accession: NM_144975
Protein: Q08AF3
(aka SLFN5_HUMAN)
CCDS: CCDS32619.1
Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.