Human Gene COQ8B (ENST00000324464.8) from GENCODE V44
Description: Homo sapiens coenzyme Q8B (COQ8B), transcript variant 1, mRNA; nuclear gene for mitochondrial product. (from RefSeq NM_024876) RefSeq Summary (NM_024876): This gene encodes a protein with two copies of a domain found in protein kinases. The encoded protein has a complete protein kinase catalytic domain, and a truncated domain that contains only the active and binding sites of the protein kinase domain, however, it is not known whether the protein has any kinase activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]. Gencode Transcript: ENST00000324464.8 Gencode Gene: ENSG00000123815.13 Transcript (Including UTRs) Position: hg38 chr19:40,691,530-40,716,886 Size: 25,357 Total Exon Count: 15 Strand: - Coding Region Position: hg38 chr19:40,692,035-40,714,632 Size: 22,598 Coding Exon Count: 14
ID:ADCK4_HUMAN DESCRIPTION: RecName: Full=Uncharacterized aarF domain-containing protein kinase 4; EC=2.7.11.-; FUNCTION: The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr). SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein (Potential). SIMILARITY: Belongs to the protein kinase superfamily. ADCK protein kinase family. SIMILARITY: Contains 1 protein kinase domain.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q96D53
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.