◀ Back to RAC1
ARF1 — RAC1
Pathways - manually collected, often from reviews:
-
NCI Pathway Database Arf1 pathway:
RAC1/GTP complex (RAC1)
→
ARF1/GTP complex (ARF1)
(modification, collaborate)
Tarricone et al., Nature 2001*
Evidence: assay, physical interaction
-
NCI Pathway Database Arf1 pathway:
RAC1/GTP complex (RAC1)
→
ARF1/GTP/Arfaptin 2 complex (ARF1-ARFIP2)
(modification, collaborate)
Tarricone et al., Nature 2001*
Evidence: assay, physical interaction
-
NCI Pathway Database Arf1 pathway:
ARF1/GTP complex (ARF1)
→
Arfaptin 2/RAC1/GTP complex (ARFIP2-RAC1)
(modification, collaborate)
Tarricone et al., Nature 2001*
Evidence: assay, physical interaction
-
NCI Pathway Database Arf1 pathway:
ARF1/GTP complex (ARF1)
→
RAC1/GDP complex (RAC1)
(modification, collaborate)
Tarricone et al., Nature 2001*
Evidence: assay, physical interaction
-
NCI Pathway Database Arf1 pathway:
ARF1/GTP complex (ARF1)
→
Arfaptin 2/RAC1/GDP complex (ARFIP2-RAC1)
(modification, collaborate)
Tarricone et al., Nature 2001*
Evidence: assay, physical interaction
-
NCI Pathway Database Arf1 pathway:
Arfaptin 2/RAC1/GTP complex (ARFIP2-RAC1)
→
ARF1/GTP/Arfaptin 2 complex (ARF1-ARFIP2)
(modification, collaborate)
Tarricone et al., Nature 2001*
Evidence: assay, physical interaction
-
NCI Pathway Database Arf1 pathway:
RAC1/GDP complex (RAC1)
→
ARF1/GTP/Arfaptin 2 complex (ARF1-ARFIP2)
(modification, collaborate)
Tarricone et al., Nature 2001*
Evidence: assay, physical interaction
-
NCI Pathway Database Arf1 pathway:
Arfaptin 2/RAC1/GDP complex (ARFIP2-RAC1)
→
ARF1/GTP/Arfaptin 2 complex (ARF1-ARFIP2)
(modification, collaborate)
Tarricone et al., Nature 2001*
Evidence: assay, physical interaction
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Conger et al., Ren Fail 1992
(Acute Kidney Injury...) :
Functionally similar ischemic
acute renal failure ( ARF ) , as estimated by glomerular filtration rates ( GFR ), was
induced by
renal artery clamping ( RAC ) or intrarenal norepinephrine ( NE ) in rats and renovascular reactivity was examined at 1 week
Santy et al., Curr Biol 2005
:
ARF6 is intimately involved in the regulation of Rac activity ; however, the mechanisms by which
ARF activation
leads to activation of
Rac remain poorly understood
Tushir et al., EMBO J 2007
:
Second,
ARF6 induced ERK activation
regulates Rac1 activation during tubule initiation through the expression of the receptor for urokinase type plasminogen activator