Gene interactions and pathways from curated databases and text-mining

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PTPN11 — SMC5

Text-mined interactions from Literome

Seki et al., Arterioscler Thromb Vasc Biol 2002 (Arteriosclerosis...) : We examined the effect of SHP2 expression on SMC proliferative activity
Wu et al., J Biol Chem 2006 : Physiologic SMC GRK5 activity also increased PDGFRbeta association with the phosphatase Shp2 ( 8-fold ), enhanced phosphorylation of PDGFRbeta Tyr ( 1009 ) ( the docking site for Shp2 ), and reduced phosphorylation of PDGFRbeta Tyr ( 1021 )