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CALM1 — HSP90AA1

Pathways - manually collected, often from reviews:

• Reactome Reaction: CALM1 → HSP90AA1 (indirect_complex) Fulton et al., Nature 1999, Dimmeler et al., Nature 1999, Michell et al., Curr Biol 1999*, Vásquez-Vivar et al., Biochem J 2002*, Berka et al., Biochemistry 2004*, García-Cardeña et al., Nature 1998*
• Reactome Reaction: CALM1 → HSP90AA1 (reaction) García-Cardeña et al., Nature 1998*

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: CALM1 — HSP90AA1 (direct interaction, pull down) Ning et al., Biochem Biophys Res Commun 1995*
• MIPS CORUM HSP90-FKBP38-CAM-Ca(2+) complex: HSP90-FKBP38-CAM-Ca(2+) complex complex (CALM2-CALM3-CALM1-FKBP8-HSP90AA1-HSP90AB1) Edlich et al., J Biol Chem 2007
• IRef Corum Interaction: Complex of CALM1-HSP90AB1-HSP90AB1-HSP90AA1-HSP90AA1-CALM1-FKBP8-FKBP8 (association, classical fluorescence spectroscopy) Edlich et al., J Biol Chem 2007
• IRef Hprd Interaction: HSP90AA1 — CALM1 (in vitro) Minami et al., J Biol Chem 1993*
• IRef Hprd Interaction: HSP90AA1 — CALM1 (in vivo) Minami et al., J Biol Chem 1993*
• IRef Intact Interaction: Complex of 90 proteins (association, tandem affinity purification) Pichlmair et al., Nature 2012
• IRef Intact Interaction: Complex of 43 proteins (association, tandem affinity purification) Pichlmair et al., Nature 2012
• IRef Intact Interaction: Complex of 171 proteins (association, anti tag coimmunoprecipitation) Sang et al., Cell 2011
• IRef Intact Interaction: Complex of 306 proteins (association, pull down) Komarova et al., Mol Cell Proteomics 2011
• IRef Intact Interaction: Complex of 156 proteins (association, anti tag coimmunoprecipitation) Lau et al., Cell 2012
• IRef Intact Interaction: Complex of 103 proteins (association, anti tag coimmunoprecipitation) Yang et al., J Proteome Res 2010
• IRef Ophid Interaction: HSP90AA1 — CALM1 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Someren et al., Biochem Biophys Res Commun 1999 : HSP-90 ( 75 or 100 nM ) significantly increased calcineurin V ( max ) in the presence of calmodulin , while maximal stimulation by HSP-70 occurred at 50 nM
Whittier et al., J Biol Chem 2004 : Hsp90 enhances degradation of oxidized calmodulin by the 20 S proteasome ... To elucidate the role of Hsp90 in promoting the degradation of oxidized calmodulin ( CaM ( ox ) ), we have purified red blood cell 20 S proteasomes free of Hsp90 and assessed their ability to degrade CaM ( ox ) in the absence or presence of Hsp90
Okano et al., J Cardiovasc Pharmacol 2006 (Body Weight) : Tyrosine phosphorylation of eNOS and expression of calmodulin increased, but Hsp90 decreased with all treatments and only raloxifene treatment increased caveolin-1 compared with OVX
Edlich et al., J Biol Chem 2007 : The Bcl-2 regulator FKBP38-calmodulin-Ca2+ is inhibited by Hsp90
Peng et al., Biochemistry 2009 : NO production by neuronal nitric oxide synthase (nNOS) requires calmodulin and is enhanced by the chaperone Hsp90 , which cycles dynamically with the enzyme
Nishida et al., J Biol Chem 1986 : Here we show that calmodulin regulates the binding of HSP90 to F-actin in a Ca2+ dependent manner ... Ca2+ dependent interaction of HSP90 with calmodulin as well as calmodulin regulated binding of HSP90 to F-actin revealed here may provide new insight into the function of HSP90 and the regulation of actin structure in cells