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CD163 — IL6

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: CD163 → IL6 (increases, IL6 Translocation)
  Evidence: Interestingly, expression of CD163, a hemoglobin/haptoglobin scavenger receptor on macrophages, is highly up-regulated by acute phase reactants, such as interleukin-6 (IL-6) and glucocorticoids (Buechler et al., 2000; Hogger and Sorg, 2001; Kristiansen et al., 2001).

Text-mined interactions from Literome

Graversen et al., Int J Biochem Cell Biol 2002 : The CD163 expression is induced by interleukin-6, interleukin-10 and glucocorticoids
Funding et al., Acta Ophthalmol Scand 2005 : To evaluate soluble CD163 ( sCD163 ) as a new marker of macrophage activity in aqueous humour from patients with corneal rejection and to investigate correlations between sCD163, the CD163 inducing interleukin-6 (IL-6) , and albumin ; to investigate whether increases in sCD163 and IL-6 levels in aqueous humour were results of intra- or extraocular production, and to investigate the impact of sCD163 and IL-6 levels on graft outcome
Franzè et al., PloS one 2013 : Functionally, interleukin-6 up-regulated CD163 expression in lamina propria mononuclear cells and mucosal explants of normal subjects