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ITGAV — MAP2K1

Text-mined interactions from Literome

Bao et al., J Cell Biol 2004 (MAP Kinase Signaling System...) : Furthermore, we found that melanoma cell integrin alphav was required for MAPK kinase ( MEK) 1 and extracellular signal regulated kinase ( ERK ) 1/2 activity in 3D-collagen, whereas inhibition of MEK1 activity induced apoptosis
Rucci et al., J Cell Sci 2005 (Bone Resorption) : Engagement of alphavbeta3 integrin triggered ERK1/2 phosphorylation, but the underlying molecular mechanism was surprisingly independent of the well known Shc/Ras/Raf-1 cascade, and of phosphorylated MAP/ERK kinase (MEK)1/2 , so far the only recognized direct activator of ERK1/2