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BRCA1 — CTBP2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Ophid Interaction: CTBP2 — BRCA1 (aggregation, confirmational text mining) Yu et al., J Biol Chem 1998*
• IRef Ophid Interaction: CTBP2 — BRCA1 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Di et al., Nature structural & molecular biology 2010 : Loss of CtBP from the BRCA1 promoter through estrogen induction, depletion by RNA interference or increased NAD+/NADH ratio leads to HDAC1 dismissal, elevated histone acetylation and increased BRCA1 transcription
May et al., Neoplasia (New York, N.Y.) 2013 (Neoplasms, Glandular and Epithelial...) : BRCA1 expression is epigenetically repressed in sporadic ovarian cancer cells by overexpression of C-terminal binding protein 2
Yu et al., J Biol Chem 1998 : This finding suggests that BRCA1 regulates gene expression, at least in part, by modulating CtBP mediated transcriptional repression