Gene interactions and pathways from curated databases and text-mining

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FGF4 — NANOG

Text-mined interactions from Literome

Xu et al., Cell stem cell 2008 : NANOG promoter activity is enhanced by TGFbeta/Activin and FGF signaling and is decreased by BMP signaling
Shi et al., J Cell Physiol 2011 : We also found that Nanog bound to the Fgf4 enhancer, and this binding was stronger in F9 cells, indicating the involvement of Nanog in the regulation of Fgf4 expression in undifferentiated and less differentiated pluripotent stem cells
Goossens et al., Stem Cells Dev 2013 : By interfering with the FGF signaling pathway, we found functional evidence that miR-218, mainly expressed in the inner cell mass, regulates the NANOG expression in the bovine blastocyst in response to FGF signaling