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FGF21 — IRS1

Text-mined interactions from Literome

Lassarre et al., Endocrinology 2003 (Breast Neoplasms) : They further suggest that the FGF induced increase in IRS-1 counterbalances the inhibition of IRS-1 tyrosine phosphorylation to allow normal stimulation of IGF-I induced PI 3-kinase activity
Li et al., Mol Cell Endocrinol 2012 : In 3T3-L1 adipocytes, the up-regulation of FGF-21markedly increased GUR, decreased intracellular triglyceride ( TG ) content, up-regulated ß-klotho, FGFR1, GLUT-1, IRS-1 , ATGL, HSL, and ap2 mRNA expressions ( p < 0.05 )