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Text-mined interactions from Literome

Yamagishi et al., Ophthalmic Res 2007 (Diabetes Mellitus, Experimental...) : However, the effects of PEDF on RAGE gene expression remain to be elucidated ... Therefore, we investigated here whether PEDF could prevent diabetes- or AGE induced RAGE gene expression and the way that it might achieve this effect ... In vitro, PEDF or an antioxidant N-acetylcysteine blocked the AGE induced RAGE gene induction in microvascular endothelial cells ... These results demonstrated that PEDF could inhibit diabetes- or AGE induced RAGE gene expression by blocking the superoxide mediated NF-kappaB activation
Ishibashi et al., Microvasc Res 2013 : PEDF or RAGE-Ab was found to inhibit the AGE induced up-regulation of RAGE mRNA level, oxidative stress generation and resultant apoptosis in podocytes