Stempin et al., Eur J Immunol 2004
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Thus, activation of TK, PKA and p38 MAPK by Cz induces an increase of arginase activity in macrophages and the subsequent T. cruzi growth
Sosroseno et al., Oral Microbiol Immunol 2006
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The effect of cAMP analog or forskolin on arginase activity in the presence or absence of A. actinomycetemcomitans LPS was blocked by the PKA inhibitor ( KT5720 )
Savchenko et al., Neurotox Res 2013
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The activation of PKA with agonist dibutyryl cAMP ( dbcAMP ) ( 100 µM ) induced the upregulation of Arg1 gene expression in microglia involving in the process of microglial activation
Corraliza et al., Biochim Biophys Acta 1997
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These results strongly suggest that PKA is involved in the induction of arginase and supports the hypothesis that there is a reciprocal regulation of these two enzymes that drives the macrophages towards opposite functional states