Gene interactions and pathways from curated databases and text-mining

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EPHB2 — MSTN

Text-mined interactions from Literome

Bish et al., PloS one 2010 : Myostatin is upregulated following stress in an Erk dependent manner and negatively regulates cardiomyocyte growth in culture and in a mouse model ... Myostatin is upregulated following cardiomyocyte stress in an Erk dependent manner that is associated with increased nuclear translocation and DNA binding activity of MEF-2
Li et al., Cell Biol Int 2011 (MAP Kinase Signaling System) : Furthermore, myostatin enhanced the phosphorylation of HSL ( hormone-sensitive lipase ) and ACC ( acetyl-CoA carboxylase ) in fully differentiated adipocytes, as well as ERK1/2