Kaneko et al., Nihon Yakurigaku Zasshi 2004
(Parkinsonian Disorders) :
Furthermore, we found that ATF6 and XBP1 that induce HRD1 promoted the degradation of Pael-R Omura et al., J Neurochem 2006
:
We also found that ATF6 overexpression, which induced HRD1, accelerated and caused Pael-R degradation ; the suppression of HRD1 expression by siRNA partially prevents this degradation