◀ Back to SMAD4
NOTCH3 — SMAD4
Text-mined interactions from Literome
Abe et al., Mech Dev 2005
:
Notch signal activation
restored the ability of C-terminal phosphorylated smad2 to bind to
smad4 , resulting in a delay in the onset of LMC
Kennard et al., J Biol Chem 2008
:
The repression of
Notch3 was
mediated by
SMAD activity and p38 mitogen activated protein ( MAP ) kinase, whereas analysis of the Hes1 promoter revealed direct activation by Smad2 but not Smad3
Fu et al., J Biol Chem 2009
:
This is the first evidence that
Notch activation
affects R-Smad expression and that cooperative induction of histone acetylation at specific promoters underlies the selective synergy between Notch and TGFbeta signaling pathways